Ask a doctor ahead of employing Roxicodone In case you are breastfeeding. Oxycodone passes into breast milk. Notify your medical professional if you discover critical drowsiness, limpness, or slow respiratory while in the nursing infant.CYP450 3A4 Interaction: The concomitant use with CYP450 3A4 inhibitors (or discontinuation of CYP450 3A4 inducers